Novel multiplex assay for profiling influenza antibodies in breast milk and serum of mother-infant pairs

NameWorld Continuing Education Alliance
Activity TitleNovel multiplex assay for profiling influenza antibodies in breast milk and serum of mother-infant pairs
DetailsThe immune system in neonates and young infants is initially immature, without adequate protection against infections. The dogma is that during infancy, systemic protection is passively provided by transplacental transfer of IgG antibodies and oral and gastrointestinal mucosal protection via breast milk (BM) containing predominantly IgA and some IgG. However, the clinical protection provided by maternal influenza immunization or exposure varies by season and the corresponding match against circulating influenza strains. Therefore, maternal influenza exposure, whether through immunization or natural infection, provides maternal protection and has the potential to imprint the infant immune system and significantly impact infant morbidity and mortality, as recently comprehensively reviewed. Maternal influenza immunization prior to or during pregnancy provides clinical protection with 70% efficiency in the infant. In this pilot study utilizing a novel multiplex assay, we assessed infant im...
CompetencePublic Health
Start Date<span class="not-set">(not set)</span>
End Date<span class="not-set">(not set)</span>
Event Time10:15 AM
LocationWorld Continuing Education Alliance eLearning System
Cost (UGX)0
CPD Points1